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Kerry: 'Do what we must' to stop Iran on nukes

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Kerry said there was a moment where Syria reached out to the West, but that moment has long past.

The hearing was an odd juxtaposition. Kerry has served on the committee during his entire 28 years in the Senate and has chaired the panel for the last four. On Thursday, he sat at the witness table, his voice at times cracking from emotion, facing his colleagues and friends.

Obama chose Kerry to succeed Secretary of State Hillary Rodham Clinton, who introduced the senator. "John is the right choice," Clinton told the panel. "He will bring a record of leadership and service that is exemplary."

Sen. Bob Menendez, D-N.J., the incoming chairman who presided over the confirmation hearing, noted that Kerry was the first senator on the panel in a century to ascend to the Cabinet post. Corker told Kerry, "you've almost lived your entire life for this moment."

A lone protester shouting about the Middle East interrupted the hearing. Just as Kerry completed his prepared testimony, the woman began shouting about the Middle East and was escorted from the room.

The Vietnam War, a long, bitter conflict that decimated a generation of draft-age men, played a prominent role at the hearing.

In his testimony, Kerry alluded to his controversial moment before the committee some 42 years ago, when the decorated Vietnam veteran testified about his opposition to the war, and famously asked, "How do you ask a man to be the last man to die for a mistake?"

"Today I can't help but recognize that the world itself then was in many ways simpler, divided as it was along bi-polar, Cold War antagonisms," Kerry said. "Today's world is more complicated than anything we have experienced — from the emergence of China to the Arab Awakening: inextricably linked economic, health, environmental and demographic issues" as well as issues such as proliferation.

McCain, who also introduced Kerry, said the roots of their friendship was their work on a committee seeking to resolve the status of POWs and missing in action from Vietnam as well as efforts to ensure normal U.S. relations with Vietnam during President Bill Clinton's administration.

Copyright 2013 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.

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